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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
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2010 3
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18 results

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Page 1
MLL-SEPTIN gene fusions in hematological malignancies.
Cerveira N, Bizarro S, Teixeira MR. Cerveira N, et al. Biol Chem. 2011 Aug;392(8-9):713-24. doi: 10.1515/BC.2011.072. Epub 2011 Jun 30. Biol Chem. 2011. PMID: 21714766 Free article. Review.
MLL fusion partners can be classified into four distinct categories: nuclear proteins, cytoplasmatic proteins, histone acetyltransferases and septins. Five different septin genes (SEPT2, SEPT5, SEPT6, SEPT9, and SEPT11) have been identified as MLL fusion partners, giving r …
MLL fusion partners can be classified into four distinct categories: nuclear proteins, cytoplasmatic proteins, histone acetyltransferases an …
Structural and expression changes of septins in myeloid neoplasia.
Cerveira N, Santos J, Teixeira MR. Cerveira N, et al. Crit Rev Oncog. 2009;15(1-2):91-115. doi: 10.1615/critrevoncog.v15.i1-2.40. Crit Rev Oncog. 2009. PMID: 20136629 Review.
Septins have been reported to be misregulated in various human diseases, including neurological disorders, infection, and neoplasia. ...Septin abnormalities in myeloid neoplasia can be divided into two major groups. First, some septins (SEPT2, SEPT5, SEPT6, SEPT9, a …
Septins have been reported to be misregulated in various human diseases, including neurological disorders, infection, and neoplasia. …
Evaluation of a Multi-Gene Methylation Blood-Test for the Detection of Colorectal Cancer.
Petit J, Carroll G, Williams H, Pockney P, Scott RJ. Petit J, et al. Med Sci (Basel). 2023 Sep 15;11(3):60. doi: 10.3390/medsci11030060. Med Sci (Basel). 2023. PMID: 37755164 Free PMC article.
The plasma was separated, and multiplex MethylLight droplet digital PCR was used to analyse for the presence of four methylated genes: SDC2, NPY, IKZF1 and SEPT9. A total of 537 participants underwent analysis. The SDC2/NPY genes showed a sensitivity of 33-54% and a specif …
The plasma was separated, and multiplex MethylLight droplet digital PCR was used to analyse for the presence of four methylated genes: SDC2, …
An MLL-SEPT9 fusion and t(11;17)(q23;q25) associated with de novo myelodysplastic syndrome.
Kreuziger LM, Porcher JC, Ketterling RP, Steensma DP. Kreuziger LM, et al. Leuk Res. 2007 Aug;31(8):1145-8. doi: 10.1016/j.leukres.2006.12.006. Epub 2007 Jan 23. Leuk Res. 2007. PMID: 17250889 Free PMC article.
Fluorescent in situ hybridization (FISH) demonstrated rearrangement of MLL, while RT-PCR analysis and sequencing identified the transcript fusion partner as SEPT9, a member of the septin family of GTPases. MLL-SEPT9 fusion appears to be rare, having been described t …
Fluorescent in situ hybridization (FISH) demonstrated rearrangement of MLL, while RT-PCR analysis and sequencing identified the transcript f …
A case of KMT2A-SEPT9 fusion-associated acute megakaryoblastic leukemia.
Forlenza CJ, Zhang Y, Yao J, Benayed R, Steinherz P, Ramaswamy K, Kessel R, Roshal M, Shukla N. Forlenza CJ, et al. Cold Spring Harb Mol Case Stud. 2018 Dec 17;4(6):a003426. doi: 10.1101/mcs.a003426. Print 2018 Dec. Cold Spring Harb Mol Case Stud. 2018. PMID: 30455225 Free PMC article.
Here we report the molecular findings of a 2-yr-old girl with AMKL and t(11;17)(q23;25) found to have a KMT2A-SEPT9 fusion identified through targeted RNA sequencing. A KMT2A-SEPT9 fusion in this subset of patients has not previously been reported....
Here we report the molecular findings of a 2-yr-old girl with AMKL and t(11;17)(q23;25) found to have a KMT2A-SEPT9 fusion identified …
Monocytic Acute Myeloid Leukemias with KM2TA Translocations to Chromosome 17q that May Clinically Mimic Acute Promyelocytic Leukemia.
Balbuena-Merle RI, Tormey CA, DiAdamo A, Rinder HM, Siddon AJ. Balbuena-Merle RI, et al. Lab Med. 2021 May 4;52(3):290-296. doi: 10.1093/labmed/lmaa078. Lab Med. 2021. PMID: 32984885
RESULTS: Both leukemias harbored KMT2A translocations, one located near but not involving RARA and the other with SEPT9. CONCLUSION: In leukemias that clinically and/or immunophenotypically mimic APL, identification of specific gene translocations can lead to the correct d …
RESULTS: Both leukemias harbored KMT2A translocations, one located near but not involving RARA and the other with SEPT9. CONCLUSION: …
Functional analysis of the SEPT9-ABL1 chimeric fusion gene derived from T-prolymphocytic leukemia.
Kawai H, Matsushita H, Suzuki R, Sheng Y, Lu J, Matsuzawa H, Yahata T, Tsuma-Kaneko M, Tsukamoto H, Kawada H, Ogawa Y, Ando K. Kawai H, et al. Leuk Res. 2014 Dec;38(12):1451-9. doi: 10.1016/j.leukres.2014.08.015. Epub 2014 Aug 30. Leuk Res. 2014. PMID: 25217890
We analyzed the function of a SEPT9-ABL1 fusion identified in a case of T-prolymphocytic leukemia with tyrosine kinase inhibitor (TKI) resistance. ...These findings demonstrated that SEPT9-ABL1 had oncogenic activity and conferred resistance to TKIs....
We analyzed the function of a SEPT9-ABL1 fusion identified in a case of T-prolymphocytic leukemia with tyrosine kinase inhibitor (TKI …
Molecular dissection of t(11;17) in acute myeloid leukemia reveals a variety of gene fusions with heterogeneous fusion transcripts and multiple splice variants.
Strehl S, König M, Meyer C, Schneider B, Harbott J, Jäger U, von Bergh AR, Loncarevic IF, Jarosova M, Schmidt HH, Moore SD, Marschalek R, Haas OA. Strehl S, et al. Genes Chromosomes Cancer. 2006 Nov;45(11):1041-9. doi: 10.1002/gcc.20372. Genes Chromosomes Cancer. 2006. PMID: 16897742
We identified six different gene fusions that comprised seven cases with a MLL-MLLT6/AF17, three with a MLL-SEPT9/MSF, and one each with MLL-LASP1, MLL-ACACA, and ZBTB16/PLZF-RARA fusions. ...The heterogeneity of transcripts encountered in cases with MLL-MLLT6/AF17 and MLL …
We identified six different gene fusions that comprised seven cases with a MLL-MLLT6/AF17, three with a MLL-SEPT9/MSF, and one each w …
18 results